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Questions and Answers about Uterine Fibroid Tumors

What are uterine fibroids?
Fibroid tumors are noncancerous (benign) growths that develop in the muscular wall of the uterus. While fibroids do not always cause symptoms, their size and location can lead to problems for some women, including pain and heavy bleeding. They typically improve after menopause when the level of estrogen, the female hormone that circulates in the blood, decreases dramatically. However, menopausal women who are taking supplemental estrogen (hormone replacement therapy) may not experience relief of symptoms.

Fibroids range in size from very tiny to the size of a cantaloupe or larger. In some cases, they can cause the uterus to grow to the size of a five -month pregnancy or more. Fibroids may be located in various parts of the uterus. There are three primary types of uterine fibroids:

Subserosal fibroids, which develop in the outer portion of the uterus and expand outward. They typically do not affect a woman’s menstrual flow, but can become uncomfortable because of their size and the pressure they cause.

Intramural fibroids, which develop within the uterine wall and expand, making the uterus feel larger than normal. These are the most common fibroids. This can result in heavier menstrual flows and pelvic pain or pressure.

Submucosal fibroids are deep within the uterus, just under the lining of the uterine cavity. These are the least common fibroids, but they often cause symptoms, including very heavy and prolonged periods.
You might hear fibroids referred to by other names, including myoma, leiomyoma, leiomyomata, and fibromyoma.

Who is most likely to have uterine fibroids?
Uterine fibroids are very common, although often they are very small and cause no problems. From 20 to 40 percent of women age 35 and older have uterine fibroids of a significant size. African American women are at a higher risk for fibroids: as many as 50 percent have fibroids of a significant size.

How are uterine fibroids diagnosed?
Fibroids are usually diagnosed during a gynecologic internal examination. Your doctor will conduct a pelvic exam to feel if your uterus is enlarged. The presence of fibroids is most often confirmed by an abdominal ultrasound. Fibroids also can be confirmed using magnetic resonance (MR) and computed tomography (CT) imaging techniques. Ultrasound, MR, and CT are painless diagnostic tests. Appropriate treatment depends on the size and location of the fibroids, as well as the severity of symptoms.

What are typical symptoms?
Depending on location, size and number of fibroids, they may cause:

  • Heavy, prolonged menstrual periods and unusual monthly bleeding, sometimes with clots. This often leads to anemia.
  • Pelvic pain
  • Pelvic pressure or heaviness
  • Pain in the back or legs
  • Pain during sexual intercourse
  • Bladder pressure leading to a constant urge to urinate
  • Pressure on the bowel, leading to constipation and bloating
  • Abnormally enlarged abdomen

How are uterine fibroids treated?
Most fibroids do not cause symptoms and are not treated. When they do cause symptoms, a drug therapy often is the first step in the treatment. This might include a prescription for birth-control pills or other hormonal therapy, or the use of non-steroidal anti-inflammatory drugs, such as ibuprofen or naproxen sodium. In many patients, symptoms are controlled with these treatments and no other therapy is required. Some hormone therapies do have a side effects and other risks when used long-term so they are generally used temporarily. Fibroids often grow back after therapy is discontinued.

The next step is to try more invasive therapy. The most common treatment options are listed below.

Surgical Treatment

Myomectomy is a surgical procedure that removes visible fibroids from the uterine wall. Myomectomy, like UFE, leaves the uterus in place and may, therefore preserve, the woman’s ability to have children. There are several ways to perform myomectomy, including hysteroscopic myomectomy, laproscopic myomectomy and abdominal myomectomy.

While myomectomy is frequently successful in controlling symptoms, the more fibroids there are in a patient’s uterus, generally, the less successful the surgery. In addition, fibroids may grow back several years after myomectomy.

Approximately one-third of the more than half-million hysterectomies performed in the United States each year are due to fibroids.

In a hysterectomy, the uterus is removed in an open surgical procedure. This operation is considered major surgery and is performed while the patient is under general anesthesia. It requires three to four days of hospitalization and the average recovery period is about six weeks. Some women are candidates for a newer laproscopic procedure. The recovery time for this procedure is considerably shorter.

Hysterectomy is the most common current therapy for women who have fibroids. It is typically performed in women who have completed their childbearing years or who understand that after the procedure they cannot become pregnant.

Minimally Invasive Treatment

Uterine Fibroid Embolization
Uterine Fibroid Embolization is a minimally invasive procedure, which means it requires only a tiny nick in the skin. It is performed while the patient is conscious but sedated – drowsy and feeling no pain.

Fibroid embolization is performed by an interventional radiologist, a physician who is specially trained to perform this and other types of embolization and minimally invasive procedures. The interventional radiologist makes a small nick in the skin (less than 1/4 of an inch) in the groin and inserts a catheter into an artery. The catheter is guided through the artery to the uterus while the interventional radiologist guides the progress of the procedure using a moving X-ray (fluoroscopy). The interventional radiologist injects tiny plastic particles the size of grains of sand into the artery that is supplying blood to the fibroid tumor. This cuts off the blood flow and causes the tumor (or tumors) to shrink. The artery on the other side of the uterus is then treated.

Fibroid embolization usually requires a hospital stay of one night. Pain-killing medications and drugs that control swelling typically are prescribed following the procedure to treat cramping and pain. Fever sometimes occurs after embolization and is usually treated with acetaminophen. Many women resume light activities in a few days and the majority of women are able to return to normal activities within one week.

While embolization to treat uterine fibroids has been performed since 1995, embolization of the uterus is not new. It has been used successfully by interventional radiologists for over 20 years to treat heavy bleeding after childbirth. The procedure is now available at hospitals and medical centers across the country.

Studies show that up to 90 percent of women who have the procedure experience significant or total relief of heavy bleeding, pain, and other symptoms. The procedure also is effective for multiple fibroids. Recurrence of treated fibroids is very rare. In one study in which patients were followed for six years, no fibroid that had been embolized regrew.

Risks associated with the treatment of fibroids.
Uterine Fibroid Embolization is considered to be very safe, however, there are some associated risks, as there are with almost any medical procedure. Most women experience moderate to severe pain and cramping in the first several hours following the procedure. Some experience nausea and fever. These symptoms can be controlled with antibiotics. It also has been reported that there is a 1 percent chance of injury to the
uterus, potentially leading to hysterectomy. These complication rates are lower than those of hysterectomy and myomectomy.

A small number of patients have entered into menopause after embolization. This is more likely to occur if the woman is in her mid-forties or older, and is already nearing menopause.

Myomectomy and hysterectomy also carry risks, including infection and bleeding leading to transfusion. Patients who undergo myomectomy may develop adhesions causing tissue and organs in the abdomen to fuse together, which can lead to infertility. In addition, the recovery time is much longer for abdominal yomectomy, generally one to two months.

You should talk with your doctor about possible risks of any procedure you may choose.

Is Uterine Fibroid Embolization right for you?
Uterine Fibroid Embolization is a Level A, American College of Obstetrics and Gynecology recommended procedure. This means it is a recognized safe and effective option in the treatment of fibroids. This procedure is appropriate for patients who would like to keep their uterus.

If you are interested in exploring your options, both surgical and minimally invasive, for alleviating symptoms associated with fibroids, University Radiology Interventional Radiologists are available to help you evaluate what procedure is right for you. Our physicians are experienced in performing Uterine Fibroid Embolizations and will help you determine if this minimally invasive procedure is the best choice based off your treatment goals.

Reprinted with permission of the Society of Interventional
Radiology© 2004, 2008, All rights reserved.
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